NCAM1/CD56 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1E8C9, Proteintech

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-6338	Proteintech Group Inc 602381IG150UL	150 μL

Description

NCAM, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig)-like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins.

Specifications

• Antigen: NCAM1/CD56
• Concentration: 0.95 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CD56, MSK39, N CAM 1, NCAM, NCAM 1, NCAM1
• Gene Symbols: Ncam1
• Isotype: IgG1
• Purification Method: Protein G
• Product Type: Antibody

• Clone: 1E8C9
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Mouse, Pig, Rat
• Gene Accession No.: P13591, P13595, P13596
• Gene ID (Entrez): 100515564, 17967, 24586, 4684
• Immunogen: NCAM1/CD56 Fusion Protein Ag5732
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: NCAM1