NCAM1/CD56 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-9321	150 μL

Catalog No. 50-172-9321 Supplier Proteintech Group Inc Supplier No. 142551AP150UL

Description

Rabbit Polyclonal Antibody

NCAM, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig)-like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins.

Specifications

• Antigen: NCAM1/CD56
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.27 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: NCAM1
• Gene Accession No.: P13591, P13595, P13596
• Gene Alias: CD56, MSK39, N CAM 1, NCAM, NCAM 1, NCAM1
• Gene Symbols: Ncam1
• Host Species: Rabbit
• Immunogen: NCAM1/CD56 Fusion Protein Ag5528
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 17967, 24586, 4684
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG