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Invitrogen™ NCAPH2 Polyclonal Antibody
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Catalog No. PIPA564393
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100 μL
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PIPA564393 100 μL
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Catalog No. PIPA564393 Supplier Invitrogen™ Supplier No. PA564393
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EAENEFLSLD DFPDSRTNVD LKNDQTPSEV LIIPLLPMAL VAPDEMEKNN NPLYSRQGEV LASRKDFRMN TCVPHPRGAF MLEPEGMS Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 82%.

Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation. A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase. The condensin I complex consists of two SMC subunits, SMC2 and SMC4, and three non-SMC subunits, CAP-H, CAP-G, and CAP-D2. An alternative complex, the condensin II complex, contains alternate non-SMC subunits, CAP-G2, CAP-H2, and CAP-D3. CAP-H2 is also known as Non-SMC condensin II complex, subunit H2 (NCAPH2) or kleisin beta isoform 2. The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex. The precise individual functions of each non-SMC protein in activation remain to be determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NCAPH2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NCAPH2
Gene Accession No. Q6IBW4
Gene Alias CAPH2; CAP-H2 subunit of the condensin II complex; Chromosome-associated protein H2; condensin-2 complex subunit H2; CTA-384D8.36; D15Ertd785e; hCAP-H2; kleisin beta; Kleisin-beta; Ncaph2; Non-SMC condensin II complex subunit H2; non-SMC condensin II complex, subunit H2
Gene Symbols NCAPH2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NCAPH2. Recombinant protein control fragment (Product #RP-103867).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29781
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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