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Invitrogen™ NCF2 Recombinant Rabbit Monoclonal Antibody (7J7N3)
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Catalog No. PIMA535393
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PIMA535393 100 μL
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Catalog No. PIMA535393 Supplier Invitrogen™ Supplier No. MA535393
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: GKATVVASVV DQDSFSGFAP LQPQAAEPPP RPKTPEIFRA LEGEAHRVLF GFVPETKEEL QVMPGNIVFV LKKGNDNWAT VMFNGQKGLV PCNYLEPVEL R.

NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). Defects in NCF2 are a cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 2 (CGD2). Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NCF2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 7J7N3
Concentration 0.55 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NCF2
Gene Accession No. A7E3N2, O70145
Gene Alias 67 kDa neutrophil oxidase factor; chronic granulomatous disease, autosomal 2; EMBL:FAA00361.1}; FLJ93058; NADPH oxidase activator 2; NADPH oxidase subunit (67 kD); NADPH oxidase subunit (67kDa); NCF2; NCF-2; ncf2 {ECO:0000312; neutrophil cytosol factor 2; neutrophil cytosolic factor 2; neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2); neutrophil NADPH oxidase factor 2; Noxa2; p67phox; p67-phox
Gene Symbols NCF2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human NOXA2/p67phox (P19878).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17970, 364018
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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