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Invitrogen™ NCF2 Polyclonal Antibody
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Catalog No. PIPA580843
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100 μL
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PIPA580843 100 μL
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Catalog No. PIPA580843 Supplier Invitrogen™ Supplier No. PA580843
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Description

Rabbit Polyclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human NCF2/NCF-2/P67phox.

NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). Defects in NCF2 are a cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 2 (CGD2). Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.
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Specifications

Antigen NCF2
Applications ELISA, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene NCF2
Gene Accession No. P19878
Gene Alias 67 kDa neutrophil oxidase factor; chronic granulomatous disease, autosomal 2; EMBL:FAA00361.1}; FLJ93058; NADPH oxidase activator 2; NADPH oxidase subunit (67 kD); NADPH oxidase subunit (67kDa); NCF2; NCF-2; ncf2 {ECO:0000312; neutrophil cytosol factor 2; neutrophil cytosolic factor 2; neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2); neutrophil NADPH oxidase factor 2; Noxa2; p67phox; p67-phox
Gene Symbols NCF2
Host Species Rabbit
Immunogen Recombinant Human NCF2/NCF-2/P67phox protein (Met1-Val526).
Purification Method Antigen affinity chromatography, Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4688
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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