Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA588253

Invitrogen™ NCF2 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA588253
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA588253 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA588253 Supplier Invitrogen™ Supplier No. PA588253
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: PPPRPKTPEI FRALEGEAHR VLFGFVPETK EELQVMPGNI VFVLKKGNDN WATVMFNGQK GLVPCNYLEP VELRIHPQQQ PQEESSPQSD IPAPPSSKAP GRPQLSPGQK QKEEPKEVKL SVPMPYTLKV HYKYTVVMKT QPGLPYSQVR DMVSKKLELR LEHTKLSYRP RDSNELVPLS EDSMKDAWGQ VKNYCLTLWC ENTVGDQGFP DEPKESEKAD ANNQTTEPQL KKGSQVEALF SYEATQPEDL EFQEGDIILV LSKVNEEWLE GECKGKVGIF PKVFVEDCAT TDLESTRREV; Positive Samples: THP-1, Mouse spleen; Cellular Location: Cytoplasm.

NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). Defects in NCF2 are a cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 2 (CGD2). Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NCF2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 7.65 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NCF2
Gene Accession No. O70145, P19878
Gene Alias 67 kDa neutrophil oxidase factor; chronic granulomatous disease, autosomal 2; EMBL:FAA00361.1}; FLJ93058; NADPH oxidase activator 2; NADPH oxidase subunit (67 kD); NADPH oxidase subunit (67kDa); NCF2; NCF-2; ncf2 {ECO:0000312; neutrophil cytosol factor 2; neutrophil cytosolic factor 2; neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2); neutrophil NADPH oxidase factor 2; Noxa2; p67phox; p67-phox
Gene Symbols NCF2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 227-526 of human NOXA2/p67phox (NP_0004242).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17970, 4688
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.