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Invitrogen™ NCF4 Polyclonal Antibody
Rabbit Polyclonal Antibody
$589.50
Specifications
| Antigen | NCF4 |
|---|---|
| Content And Storage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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PIPA5111070
|
Invitrogen™
PA5111070 |
100 μL |
Each for $589.50
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PIPA5111462
|
Invitrogen™
PA5111462 |
100 μL |
Each for $589.50
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Description
Immunogen sequence: MAVAQQLRAE SDFEQLPDDV AISANIADIE EKRGFTSHFV FVIEVKTKGG SKYLIYRRY.
The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.Specifications
| NCF4 | |
| Immunohistochemistry (Paraffin) | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q15080 | |
| 4689 | |
| Recombinant Protein corresonding to Human NCF4. Recombinant protein control fragment (Product #RP-95361). | |
| Antibody |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human | |
| Ncf4 | |
| AI451400; CGD3; CTA-833B7.1; MGC3810; NCF; Ncf4; NCF-4; Neutrophil cytosol factor 4; neutrophil cytosolic factor 4; neutrophil cytosolic factor 4, 40kDa; neutrophil NADPH oxidase factor 4; OTTHUMP00000028736; OTTHUMP00000043756; P40PHOX; p40-phox; SH3 and PX domain-containing protein 4; SH3PXD4 | |
| Ncf4 | |
| Primary | |
| Antigen affinity chromatography |
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