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Invitrogen™ NCK2 Polyclonal Antibody
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Catalog No. PIPA529210
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100 μL
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PIPA529210 100 μL
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Catalog No. PIPA529210 Supplier Invitrogen™ Supplier No. PA529210
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Rabbit Polyclonal Antibody

Recommended positive controls: A549, HepG2. Predicted reactivity: Mouse (95%), Rat (95%), Xenopus laevis (83%), Pig (90%), Chicken (92%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The NCK family of SH2/SH3 adaptor proteins consists of two members, NCK1 and NCK2, which couple tyrosine kinase signaling, including the EGF and PDGF receptor-pathways, to downstream signaling proteins. The NCK2 protein binds human PDGFR-b (Tyr-1009); overexpression of NCK2 inhibits PDGF-induced membrane ruffling and lamellipod formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NCK2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene NCK2
Gene Accession No. O43639
Gene Alias 4833426I10Rik; cytoplasmic protein NCK2; Grb4; growth factor receptor-bound protein 4; NCK adaptor protein 2; NCK2; Nck-2; NCKbeta; non-catalytic region of tyrosine kinase adaptor protein 2; noncatalytic region of tyrosine kinase, beta; SH2/SH3 adaptor protein NCK-beta
Gene Symbols NCK2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Nck beta. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8440
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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