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Tocris Bioscience™ NCL 00017509
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Catalog No. 51501
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Quantity:
1 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and reversible NIMA related kinase 2 (Nek2) inhibitor

NCL 00017509 is a potent and reversible NIMA related kinase 2 (Nek2) inhibitor (IC50 = 56 nM). Induces increased mitotic abnormalities and mitotic delay. Cell permeable and active in vivo. In mice bearing pancreatic tumors, NCL 00017509 decreases PD-L1 expression and induces an anticancer immune response.

Chemical Identifiers

CAS 1507367-00-1
Molecular Formula C15H12N6O

Specifications

Quantity 1 mg
Solubility Soluble to 100mM in DMSO
Formula Weight 292.3
Physical Form Solid
Purity >97%
Molecular Weight (g/mol) 292.302
Chemical Name or Material 3-[(6-Ethynyl-9H-purin-2-yl)amino]benzeneacetamide

Safety and Handling

Recommended Storage Store at -20°C
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