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NCLN Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501570891
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20 μL; Unconjugated
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Catalog No.
50-157-0891 20 μL; Unconjugated
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Catalog No. 50-157-0891 Supplier Bethyl Laboratories, Inc Supplier No. A305623AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Nicalin, along with its binding partner Nomo, is a novel signaling antagonist to Nodals, signaling factors of the TGF-Beta superfamily that play a key role in vertebrate development. Nicalin is distantly related to Nicastrin, a component of the Alzheimer′s disease-associated gamma-secretase, and is thought to have a similar function. Another protein, TMEM147, has also been recently identified as associating with Nicalin and NOMO as part of the gamma-secretase-like complex.

Specifications

Antigen NCLN
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene NCLN
Gene Accession No. Q8VCM8, Q969V3
Gene Alias NET59, nicalin homolog (zebrefish), nicastrin-like protein
Gene Symbols Ncln
Host Species Rabbit
Immunogen Between 375 and 425
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 103425, 56926
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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