NCLN Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A305623AT

Catalog No. 50-157-0891

Description

The recommended shelf life for this product is 1 year from date of receipt.

Nicalin, along with its binding partner Nomo, is a novel signaling antagonist to Nodals, signaling factors of the TGF-Beta superfamily that play a key role in vertebrate development. Nicalin is distantly related to Nicastrin, a component of the Alzheimer′s disease-associated gamma-secretase, and is thought to have a similar function. Another protein, TMEM147, has also been recently identified as associating with Nicalin and NOMO as part of the gamma-secretase-like complex.

Specifications

• Antigen: NCLN
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: Q8VCM8, Q969V3
• Gene Symbols: Ncln
• Immunogen: Between 375 and 425
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Gene: NCLN
• Gene Alias: NET59, nicalin homolog (zebrefish), nicastrin-like protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 103425, 56926
• Content And Storage: 4° C
• Form: Liquid