Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIMA537555

Invitrogen™ NCOA4 Monoclonal Antibody (439CT10.4.4)
GREENER_CHOICE

Catalog No. PIMA537555
Change view
Click to view available options
Quantity:
400 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIMA537555 400 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIMA537555 Supplier Invitrogen™ Supplier No. MA537555
Only null left
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

NCOA4 Monoclonal Antibody for Western Blot

Androgen receptor (AR) coactivator ARA70, also designated NCOA4, RFG and ELE1, is a putative co-activator that specifically enhances the activity of the androgen receptor. In human thyroid carcinomas, the Ret proto-oncogene fuses to ARA70 to form Ret/PTC3 by an intrachromosomal inversion of chromosome in vivo. ARA70 is expressed as two isoforms, ARA70a and ARA70b. The shorter variant, ARA70b, results from an internal 985-bp deletion. ARA70a is widely expressed, and its expression is highest in testis and adipose tissues, whereas ARA70b is solely expressed in the testis. ARA70a can function as a ligand-enhanced co-activator of PPARg in adipocytes. ARA70 may be involved in prostate carcinogenesis and ovarian cancer and may serve as a key mediator of estrogen-androgen synergism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NCOA4
Applications Western Blot
Classification Monoclonal
Clone 439CT10.4.4
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene NCOA4
Gene Accession No. Q13772
Gene Alias 70 kDa androgen receptor coactivator; 70 kDa AR-activator; Androgen receptor coactivator 70 kDa protein; Androgen receptor-associated protein of 70 kDa; ARA70; ELE1; NCOA4; NCoA-4; Nuclear receptor coactivator 4; PTC3; ret fused; RET-activating gene ELE1; Ret-activating protein ELE1; RFG
Gene Symbols NCOA4
Host Species Mouse
Immunogen purified His-tagged NCOA4 protein (fragment).
Purification Method Euglobulin precipitation
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8031
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgM
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.