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Invitrogen™ NCOA6 Polyclonal Antibody
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Catalog No. PIPA552071
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100 μL
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PIPA552071 100 μL
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Catalog No. PIPA552071 Supplier Invitrogen™ Supplier No. PA552071
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Rabbit Polyclonal Antibody

Immunogen sequence: NQNVQHAGGQ GAGPPQNQMQ VSHGPPNMMQ PSLMGIHGNM NNQQAGTSGV PQVNLSNMQG QPQQGPPSQL MGMHQQIVPS QGQMVQQQGT LNPQNPMILS RAQLMPQGQM MVNPPSQNLG PSPQRMTPPK Q Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%.

Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NCOA6
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NCOA6
Gene Accession No. Q14686
Gene Alias activating signal cointegrator 2; activating signal cointegrator-2; AIB3; Amplified in breast cancer protein 3; amplified in breast cancer-3 protein; ASC2; ASC-2; Cancer-amplified transcriptional coactivator ASC-2; KIAA0181; mKIAA0181; NCOA6; Ncoa7; NRC; NRC RAP250; nuclear receptor coactivator 6; Nuclear receptor coactivator RAP250; nuclear receptor-activating protein 250; nuclear receptor-activating protein, 250 kDa; peroxisome proliferator-activated receptor interacting protein; peroxisome proliferator-activated receptor interacting protein,PRIP; peroxisome proliferator-activated receptor-interacting protein; PPAR interacting protein PRIP; PPAR-interacting protein; PRIP; RAP250; thyroid hormone receptor binding protein; thyroid hormone receptor-binding protein; TRBP
Gene Symbols NCOA6
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NCOA6. Recombinant protein control fragment (Product #RP-102323).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23054
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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