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Invitrogen™ NCoR2 Monoclonal Antibody (1212)
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Catalog No. PIMA531591
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100 μL
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Catalog No. Quantity
PIMA531591 100 μL
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Catalog No. PIMA531591 Supplier Invitrogen™ Supplier No. MA531591
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Description

Mouse Monoclonal Antibody

Keep as concentrated solution. Positive Control: HBL100.

Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate. Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR) are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NCoR2
Applications ChIP Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot, Western Blot
Classification Monoclonal
Clone 1212
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene NCOR2
Gene Accession No. Q9Y618
Gene Alias CTG repeat protein 26; CTG26; N-CoR; NCOR2; N-CoR2; nuclear receptor corepressor; nuclear receptor corepressor 2; nuclear receptor co-repressor 2; silencing mediator for retinoid and thyroid hormone receptors; silencing mediator of retinoic acid and thyroid hormone receptor; silencing mediator of retinoid acid and thyroid hormone receptor; SMAP270; SMRT; SMRTe; SMRTE-tau; T3 receptor-associating factor; Thyroid-, retinoic-acid-receptor-associated corepressor; TNRC14; TRAC; TRAC1; TRAC-1
Gene Symbols NCOR2
Host Species Mouse
Immunogen A synthetic peptide from the human SMRT protein corresponding to amino acids 994-1005 (ASASDPHREKTQ) coupled to KLH.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9612
Target Species Human, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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