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NCR2 Mouse anti-Human, Clone: OTI4B8, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF809536

Catalog No. 50-166-9567


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

CD336 is also known as NKp44 or NCR2. CD336 is a 44-kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family and contains an ITIM domain located in the cytoplasmic tail. Expression of CD336 and NK cell activation by the receptor requires association with DAP12, an ITAM-containing transmembrane accessory protein. Once thought to be expressed exclusively on IL-2-activated NK cells and a subset of gamma delta T lymphocytes, studies have shown expression of CD336 on IL-3-stimulated plasmacytoid dendritic cells, alpha beta T cells in the small intestinal epithelium, and T cells in cord blood. CD336 has been shown to be involved in the innate response of activated NK cells against viral infection and tumor cell proliferation.
Specifications

Specifications

NCR2
Monoclonal
Unconjugated
NCR2
Lyophilized
NCR2
Human recombit protein fragment corresponding to amino acids 44-190 of human NCR2 produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin), Western Blot
OTI4B8
PBS with 8% trehalose and no preservative; pH 7.3
O95944
CD336, LY95, NK-p44, NKP44, dJ149M18.1
Mouse
IgG2b
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
9436
SDS
Documents
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