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  5. Tocris Bioscience™ NCT 02

Tocris Bioscience™ NCT 02
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Catalog No. 755110
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Catalog No. Quantity
75-511-0 10 mg
75-515-0 50 mg
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Catalog No. 75-511-0 Supplier Tocris Bioscience™ Supplier No. 7551/10
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Description

Molecular glue; induces degradation of CCNK and CDK12

NCT 02 acts as a molecular glue that induces proteasomal degradation of CCNK and CDK12 in colorectal cancer spheroid cells in vitro (IC50 ≤ 50 μM). NCT 02 also induces apoptosis and the downregulation of genes involved in DNA damage repair.

Specifications

Chemical Name or Material 6,7-Dihydro-N-(5-methyl-2-thiazolyl)-5 H-indeno[5,6-b]furan-3-acetamide
CAS 790245-61-3
Quantity 10 mg
Target Molecular Glues
Molecular Formula C17H16N2O2S
Purity 0.98
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