Invitrogen™ NDFIP1 Monoclonal Antibody (N1Nterm15-328)

Hamster Monoclonal Antibody

Supplier:  Invitrogen™ MA546562

Catalog No. PIMA546562

Description

Predicted molecular weight: 25 kDa.

The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.

Specifications

• Antigen: NDFIP1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q8R0W6
• Gene Symbols: NDFIP1
• Immunogen: N-terminal peptide of murine Ndfip 1 coupled to KLH (VEPACGSGYQQLQNEEPGE) (aa 11-30).
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Western Blot
• Clone: N1Nterm15-328
• Conjugate: Unconjugated
• Gene: NDFIP1
• Gene Alias: 0610010M22Rik; Breast cancer-associated protein SGA-1M; N4wbp5; Ndfip1; Nedd4 family interacting protein 1; NEDD4 family-interacting protein 1; Nedd4 WW binding protein 5; NEDD4 WW domain-binding protein 5; Nedd4 WW-binding protein 5; PSEC0192; PSEC0223; Putative MAPK-activating protein PM13; putative NF-kappa-B-activating protein 164; Putative NFKB and MAPK-activating protein
• Host Species: Hamster
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 65113
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid