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Invitrogen™ NDFIP1 Monoclonal Antibody (N1Nterm15-328)
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Catalog No. PIMA546562
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Quantity:
50 μg
Catalog No. Quantity
PIMA546562 50 μg
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Catalog No. PIMA546562

Supplier: Invitrogen™ MA546562

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Description

Hamster Monoclonal Antibody

Predicted molecular weight: 25 kDa.

The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NDFIP1
Applications ELISA, Western Blot
Classification Monoclonal
Clone N1Nterm15-328
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene NDFIP1
Gene Accession No. Q8R0W6
Gene Alias 0610010M22Rik; Breast cancer-associated protein SGA-1M; N4wbp5; Ndfip1; Nedd4 family interacting protein 1; NEDD4 family-interacting protein 1; Nedd4 WW binding protein 5; NEDD4 WW domain-binding protein 5; Nedd4 WW-binding protein 5; PSEC0192; PSEC0223; Putative MAPK-activating protein PM13; putative NF-kappa-B-activating protein 164; Putative NFKB and MAPK-activating protein
Gene Symbols NDFIP1
Host Species Hamster
Immunogen N-terminal peptide of murine Ndfip 1 coupled to KLH (VEPACGSGYQQLQNEEPGE) (aa 11-30).
Purification Method Protein G
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 65113
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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