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Invitrogen™ NDFIP1 Polyclonal Antibody
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Catalog No. PIPA5101992
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PIPA5101992 100 μL
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Catalog No. PIPA5101992 Supplier Invitrogen™ Supplier No. PA5101992
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NDFIP1.

The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NDFIP1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NDFIP1
Gene Accession No. Q5U2S1, Q8R0W6, Q9BT67
Gene Alias 0610010M22Rik; Breast cancer-associated protein SGA-1M; N4wbp5; Ndfip1; Nedd4 family interacting protein 1; NEDD4 family-interacting protein 1; Nedd4 WW binding protein 5; NEDD4 WW domain-binding protein 5; Nedd4 WW-binding protein 5; PSEC0192; PSEC0223; Putative MAPK-activating protein PM13; putative NF-kappa-B-activating protein 164; Putative NFKB and MAPK-activating protein
Gene Symbols NDFIP1
Host Species Rabbit
Immunogen A synthesized peptide derived from human NDFIP1(Accession Q9BT67), corresponding to amino acid residues Y178-Y221.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 291609, 65113, 80762
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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