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Invitrogen™ NDFIP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101992

Catalog No. PIPA5101992


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Description

Description

Antibody detects endogenous levels of total NDFIP1.

The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

NDFIP1
Polyclonal
Unconjugated
NDFIP1
0610010M22Rik; Breast cancer-associated protein SGA-1M; N4wbp5; Ndfip1; Nedd4 family interacting protein 1; NEDD4 family-interacting protein 1; Nedd4 WW binding protein 5; NEDD4 WW domain-binding protein 5; Nedd4 WW-binding protein 5; PSEC0192; PSEC0223; Putative MAPK-activating protein PM13; putative NF-kappa-B-activating protein 164; Putative NFKB and MAPK-activating protein
Rabbit
Affinity Chromatography
RUO
291609, 65113, 80762
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q5U2S1, Q8R0W6, Q9BT67
NDFIP1
A synthesized peptide derived from human NDFIP1(Accession Q9BT67), corresponding to amino acid residues Y178-Y221.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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