Invitrogen™ NDFIP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534421

Catalog No. PIPA534421

Description

A suggested positive control is PC-3 cell lysate. PA5-34421 can be used with blocking peptide PEP-1463.

The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.

Specifications

• Antigen: NDFIP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NDFIP1
• Gene Alias: 0610010M22Rik; Breast cancer-associated protein SGA-1M; N4wbp5; Ndfip1; Nedd4 family interacting protein 1; NEDD4 family-interacting protein 1; Nedd4 WW binding protein 5; NEDD4 WW domain-binding protein 5; Nedd4 WW-binding protein 5; PSEC0192; PSEC0223; Putative MAPK-activating protein PM13; putative NF-kappa-B-activating protein 164; Putative NFKB and MAPK-activating protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 65113, 80762
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q8R0W6, Q9BT67
• Gene Symbols: NDFIP1
• Immunogen: A 19 amino acid synthetic peptide near the amino terminus of human NDFIP1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov