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NDFIP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550172

Catalog No. PA550172


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Description

Description

The antibody detects endogenous levels of total NDFIP1 protein.

The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.
Specifications

Specifications

NDFIP1
Polyclonal
Unconjugated
NDFIP1
Liquid
NDFIP1
Synthesized peptide derived from C-terminal of human NDFIP1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q9BT67, Q8R0W6, Q5U2S1
N4WBP5
Rabbit
IgG
100 μL
-20°C
Primary
291609, 65113, 80762
Documents
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