NDFIP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-0341	Proteintech Group Inc 156021AP150UL	150 μL

Description

The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.

Specifications

• Antigen: NDFIP1
• Applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q5U2S1, Q8R0W6, Q9BT67
• Gene ID (Entrez): 291609, 65113, 80762
• Immunogen: NDFIP1 Fusion Protein Ag7985
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: NDFIP1

• Concentration: 0.23 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: N4WBP5, NDFIP1, PSEC0223
• Gene Symbols: Ndfip1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody