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NDFIP2 Mouse anti-Human, Clone: 2C7, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524465

Catalog No. PIMA524465


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Description

Description

Peptide Sequence: MDHHQPGTGR YQVLLNEEDN SESSAIEQPP TSNPAPQIVQ AASSAPALET DSSPPPYSSI TVEVPTTSDT EVYGEFYPVP PPYSVATSLP TYDEAEKAKA AAMAAAAAET SQRIQEEECP PRDDFSDADQ LRVGNDGIFM LAFFMAFIFN WLGFCLSFCI TNTIAGRYGA ICGFGLSLIK WILIVRFSDY FTGYFNGQYW LWWIFLVLGL LLFFRGFVNY LKVRNMSESM AAAHRTRYFF LL

Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. May modulate EGFR signaling.
Specifications

Specifications

NDFIP2
Monoclonal
Unconjugated
NDFIP2
Liquid
NDFIP2
NDFIP2 (AAH21988, 1 a.a. ∽ 242 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Protein A
RUO
Antibody
Monoclonal
Human
ELISA, Western Blot
2C7
PBS with no preservative; pH 7.4
Q9NV92
NDFIP2; KIAA1165; N4WBP5A
Mouse
IgG2a, kappa
100 μg
-20° C
Primary
54602
Documents
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