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Invitrogen™ NDNL2 Polyclonal Antibody
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Catalog No. PA550619
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PA550619 100 μL
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Catalog No. PA550619 Supplier Invitrogen™ Supplier No. PA550619
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total HCA-4 protein.

The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs).
TRUSTED_SUSTAINABILITY

Specifications

Antigen NDNL2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene NSMCE3
Gene Accession No. Q96MG7, Q9CPR8
Gene Alias 5730494G16Rik; AI642138; BB044375; HCA4; Hepatocellular carcinoma-associated protein 4; hepatocellular carcinoma-associated protein HCA4; Mageg1; mage-g1; MAGE-G1 antigen; MAGEL3; magg1; melanoma antigen, family G, 1; melanoma-associated antigen G1; NDNL2; necdin-like 2; necdin-like 2, SMC5-SMC6 complex component; necdin-like gene 2; necdin-like protein 2; Non-SMC element 3 homolog; non-structural maintenance of chromosomes element 3 homolog; NSE3; NSE3 homolog, SMC5-SMC6 complex component; NSMCE3
Gene Symbols NSMCE3
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues near the C terminal of human necdin-like 2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56160, 66647
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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