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Invitrogen™ NDST1 Polyclonal Antibody
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Catalog No. PIPA563871
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100 μL
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PIPA563871 100 μL
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Catalog No. PIPA563871 Supplier Invitrogen™ Supplier No. PA563871
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YEPVLLAKTR SSESIPHLGA DAGLHAALHA TVVQ Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L- selectin ligands, thereby playing a role in inflammatory response.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NDST1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NDST1
Gene Accession No. P52848
Gene Alias [Heparan sulfate]-glucosamine N-sulfotransferase 1; 1200015G06Rik; b2b2230Clo; bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1; Glucosaminyl N-deacetylase/N-sulfotransferase 1; Heparan sulfate N-deacetylase 1; Heparan sulfate N-sulfotransferase 1; heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase 1; heparan sulfate-N-deacetylase/N-sulfotransferase; HSNST 1; HSST; HSST1; MRT46; N-deacetylase and N-sulfotransferase 1; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1; N-deacetylase/N-sulfotransferase 1; N-deacetylase/N-sulfotransferase-1; N-Deacetylase-N-sulfotransferase 1; Ndst1; NDST-1; N-heparan sulfate sulfotransferase 1; N-HSST 1; NST1
Gene Symbols NDST1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NDST1. Recombinant protein control fragment (Product #RP-103376).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3340
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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