Invitrogen™ NDST1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563871

Catalog No. PIPA563871

Description

Immunogen sequence: YEPVLLAKTR SSESIPHLGA DAGLHAALHA TVVQ Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L- selectin ligands, thereby playing a role in inflammatory response.

Specifications

• Antigen: NDST1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NDST1
• Gene Alias: [Heparan sulfate]-glucosamine N-sulfotransferase 1; 1200015G06Rik; b2b2230Clo; bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1; Glucosaminyl N-deacetylase/N-sulfotransferase 1; Heparan sulfate N-deacetylase 1; Heparan sulfate N-sulfotransferase 1; heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase 1; heparan sulfate-N-deacetylase/N-sulfotransferase; HSNST 1; HSST; HSST1; MRT46; N-deacetylase and N-sulfotransferase 1; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1; N-deacetylase/N-sulfotransferase 1; N-deacetylase/N-sulfotransferase-1; N-Deacetylase-N-sulfotransferase 1; Ndst1; NDST-1; N-heparan sulfate sulfotransferase 1; N-HSST 1; NST1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3340
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P52848
• Gene Symbols: NDST1
• Immunogen: Recombinant protein corresponding to Human NDST1. Recombinant protein control fragment (Product #RP-103376).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG