NDST1 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS9891R

Catalog No. 50-198-9429

Description

Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L- selectin ligands, thereby playing a role in inflammatory response.

Specifications

• Antigen: NDST1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NDST1
• Gene Alias: [Heparan sulfate]-glucosamine N-sulfotransferase 1; 1200015G06Rik; b2b2230Clo; Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1; Glucosaminyl N-deacetylase/N-sulfotransferase 1; Heparan sulfate N-deacetylase 1; Heparan sulfate N-sulfotransferase 1; heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase 1; heparan sulfate-N-deacetylase/N-sulfotransferase; HSNST 1; HSST; HSST1; MRT46; N-deacetylase and N-sulfotransferase 1; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1; N-deacetylase/N-sulfotransferase 1; N-deacetylase/N-sulfotransferase-1; N-Deacetylase-N-sulfotransferase 1; Ndst1; NDST-1; N-heparan sulfate sulfotransferase 1; N-HSST 1; NST1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3340
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P52848
• Gene Symbols: NDST1
• Immunogen: KLH conjugated synthetic peptide derived from human NDST1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG