Invitrogen™ NDUFA12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596981

Catalog No. PIPA596981

Description

Immunogen sequence: MELVQVLKRG LQQITGHGGL RGYLRVFFRT NDAKVGTLVG EDKYGNKYYE DNKQFFGRHR WVVYTTEMNG KNTFWDVDGS MVPPEWHRWL HSMTDDPPTT KPLTARKFIW TNHKFNVTGT PEQYVPYSTT RKKIQEWIPP STPYK; Positive Samples: 293T, PC-12, HepG2, Mouse kidney, Mouse heart, Mouse testis, Rat heart, Rat brain; Cellular Location: Matrix side, Mitochondrion inner membrane, Peripheral membrane protein.

This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: NDUFA12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ndufa12
• Gene Alias: 13 kDa differentiation-associated protein; 13kDa differentiation-associated protein; 2410011G03Rik; AW112974; B17.2; CIB17.2; CI-B17.2; complex I B17.2 subunit; complex I-B17.2; DAP13; DAP13 protein; hypothetical protein LOC613140; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; NADH:ubiquinone oxidoreductase b17.2 subunit; NADH:ubiquinone oxidoreductase subunit A12; NADH-ubiquinone oxidoreductase subunit B17.2; Ndufa12; RGD1311462; si:dkey-183c16.3; zgc:112053
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 299739, 55967, 66414
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.32 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q7TMF3, Q9UI09
• Gene Symbols: Ndufa12
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human NDUFA12 (NP_0613261).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG