Invitrogen™ NDUFA13 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA14272

Catalog No. PA14272

Description

PA1-4272 detects the GRIM-19 protein in human, mouse, and rat samples. PA1-4272 has been successfully used in Western blot procedures. PA1- 4272 immunizing peptide corresponds to amino acid residues 159-172 of the human GRIM-19 protein.

A novel gene associated with Retinoid-IFN-induced Mortality (GRIM) GRIM-19 gene was identified. Antisense expression of GRIM-19 confers a strong resistance against IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein. Overexpression of GRIM-19 enhances cell death in response to IFN/RA. GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM-19 is a novel cell death-regulatory molecule.

Specifications

• Antigen: NDUFA13
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ndufa13
• Gene Alias: 2700054G14Rik; AU022060; B16.6; CDA016; Cell d; Cell death regulatory protein GRIM-19; cell death-regulatory protein GRIM19; CGI-39; CI-B16.6; complex I B16.6 subunit; complex I-B16.6; FLJ58045; FLJ59191; gene associated with retinoic and IFN-induced mortality 19 protein; gene associated with retinoic and interferon-induced mortality 19 protein; Gene associated with retinoic-interferon-induced mortality 19 protein; genes associated with retinoid-IFN-induced mortality 19; GRIM19; GRIM-19; LOC100911483; mitochondrial NADH:ubiquinone oxidoreductase B16.6 subunit; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13-like; NADH:ubiquinone oxidoreductase subunit A13; NADH-ubiquinone oxidoreductase B16.6 subunit; Ndufa13; YjeF N-terminal domain-containing protein 3; YjeF_N3; Yjefn3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100911483, 314759, 51079, 67184
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q9ERS2, Q9P0J0
• Gene Symbols: Ndufa13, Ndufa13-ps1
• Immunogen: Synthetic peptide: Q(159) A E T D R R T L Q M L R E(172).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG