Invitrogen™ NDUFA13 Recombinant Rabbit Monoclonal Antibody (7D1Z6)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535402

Catalog No. PIMA535402

Description

Immunogen sequence: MAASKVKQDM PPPGGYGPID YKRNLPRRGL SGYSMLAIGI GTLIYGHWSI MKWNRERRRL QIEDFEARIA LLPLLQAETD RRTLQMLREN LEEEAIIMKD VPDWKVGESV FHTTRWVPPL IGELYGLRTT EEALHASHGF MWYT.

A novel gene associated with Retinoid-IFN-induced Mortality (GRIM) GRIM-19 gene was identified. Antisense expression of GRIM-19 confers a strong resistance against IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein. Overexpression of GRIM-19 enhances cell death in response to IFN/RA. GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM-19 is a novel cell death-regulatory molecule.

Specifications

• Antigen: NDUFA13
• Classification: Recombinant Monoclonal
• Concentration: 1.7 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9P0J0
• Gene Symbols: Ndufa13
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human NDUFA13/GRIM19 (Q9P0J0) (NP_057049.5).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 7D1Z6
• Conjugate: Unconjugated
• Gene: Ndufa13
• Gene Alias: 2700054G14Rik; AU022060; B16.6; CDA016; Cell d; Cell death regulatory protein GRIM-19; cell death-regulatory protein GRIM19; CGI-39; CI-B16.6; complex I B16.6 subunit; complex I-B16.6; FLJ58045; FLJ59191; gene associated with retinoic and IFN-induced mortality 19 protein; gene associated with retinoic and interferon-induced mortality 19 protein; Gene associated with retinoic-interferon-induced mortality 19 protein; genes associated with retinoid-IFN-induced mortality 19; GRIM19; GRIM-19; LOC100911483; mitochondrial NADH:ubiquinone oxidoreductase B16.6 subunit; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13-like; NADH:ubiquinone oxidoreductase subunit A13; NADH-ubiquinone oxidoreductase B16.6 subunit; Ndufa13; YjeF N-terminal domain-containing protein 3; YjeF_N3; Yjefn3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51079
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid