Invitrogen™ NDUFB11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590580

Catalog No. PIPA590580

Description

Immunogen sequence: MAAGLFGLSA RRLLAAAATR GLPAARVRWE SSFSRTVVAP SAVAGKRPPE PTTPWQEDPE PEDENLYEKN PDSHGYDKDP VLDVWNMRLV FFFGVSIILV LGSTFVAYLP DYRCTGCPRA WDGMKEWSRR EAERLVKYRE ANGLPIMESN CFDPSKIQLP EDE; Positive Samples: HepG2, U-251MG, K-562, HeLa, Mouse liver, Mouse heart, Rat brain, Rat liver.

NDUFB11 is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. NDUFB11 functions in the transfer of electrons from NADH to the respiratory chain and is located in the inner mitochondrial membrane. The immediate electron acceptor for NDUFB11 is believed to be ubiquinone. Further, NDUFB11 is believed to have NADH dehydrogenase activity, and oxidoreductase activity. Diseases associated with NDUFB11 protein dysfunction include linear skin defects with multiple congenital anomalies and mitochondrial complex I deficiency.

Specifications

• Antigen: NDUFB11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NDUFB11
• Gene Alias: CI-ESSS; complex I NP17.3 subunit; complex I-ESSS; D5Bwg0566e; D5Bwg0577e; ESSS; LSDMCA3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial; NADH:ubiquinone oxidoreductase subunit B11; NADH-ubiquinone oxidoreductase ESSS subunit; NDUFB11; Neuronal protein 15.6; neuronal protein 17.3; Np15; NP15.6; Np17.3; nuclear protein 15.6; p15.6; P17.3; RGD1563698; UNQ111/PRO1064
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 104130, 299310, 54539
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.11 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O09111, Q9NX14
• Gene Symbols: NDUFB11
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-163 of human NDUFB11 (NP_0619292).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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