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Invitrogen™ NDUFS1 Polyclonal Antibody
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Catalog No. PIPA528220
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100 μL
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PIPA528220 100 μL
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Catalog No. PIPA528220 Supplier Invitrogen™ Supplier No. PA528220
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HepG2, mouse brain, rat brain. Predicted reactivity: Mouse (91%), Rat (92%), Xenopus laevis (82%), Chicken (86%), Chimpanzee (99%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NDUFS1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.20 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene NDUFS1
Gene Accession No. P28331, Q66HF1, Q91VD9
Gene Alias 5830412M15Rik; 9930026A05Rik; CI-75k; CI-75kD; complex I 75kDa subunit; complex I, mitochondrial respiratory chain, 75-kD subunit; complex I-75kD; MGC26839; mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit; NADH dehydrogenase (ubiquinone) Fe-S protein 1; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase); NADH:ubiquinone oxidoreductase core subunit S1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; NDUFS1; NDUFS-1; OTTHUMP00000206345; PRO1304
Gene Symbols NDUFS1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human NDUFS1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 227197, 301458, 4719
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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