NDUFS1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA528220

Catalog No. PIPA528220

Description

Recommended positive controls: HepG2, mouse brain, rat brain. Predicted reactivity: Mouse (91%), Rat (92%), Xenopus laevis (82%), Chicken (86%), Chimpanzee (99%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: NDUFS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NDUFS1
• Gene Alias: 5830412M15Rik; 9930026A05Rik; CI-75k; CI-75kD; complex I 75kDa subunit; complex I, mitochondrial respiratory chain, 75-kD subunit; complex I-75kD; MGC26839; mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit; NADH dehydrogenase (ubiquinone) Fe-S protein 1; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase); NADH:ubiquinone oxidoreductase core subunit S1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; NDUFS1; NDUFS-1; OTTHUMP00000206345; PRO1304
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 227197, 301458, 4719
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.20 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P28331, Q66HF1, Q91VD9
• Gene Symbols: NDUFS1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 312 and 642 of Human NDUFS1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov