Invitrogen™ NDUFS2 Monoclonal Antibody (OTI2G2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526534

Catalog No. PIMA526534

Description

NDUFS2 Monoclonal Antibody for Western Blot, IHC (P)

The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase. Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: NDUFS2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O75306
• Gene Symbols: Ndufs2
• Immunogen: Human recombinant protein fragment corresponding to amino acids 205-463 of NDUFS2 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2G2
• Conjugate: Unconjugated
• Gene: Ndufs2
• Gene Alias: AL033311; CI-49; CI-49kD; comp; complex 1, mitochondrial respiratory chain, 49-KD subunit; complex I 49kDa subunit; complex I-49kD; EMBL:AAH82067.1}; NADH dehydrogenase (ubiquinone) Fe-S protein 2; NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; NADH:ubiquinone oxidoreductase core subunit S2; NADH-coenzyme Q reductase; NADH-ubiquinone oxidoreductase 49 kDa subunit; NADH-ubiquinone oxidoreductase NDUFS2 subunit; Ndufs2; ndufs2 {ECO:0000312; unnamed protein product
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4720
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid