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NDUFS5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501730079 Shop All Proteintech Group Inc Products
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50-173-0079 150 μL
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Catalog No. 50-173-0079 Supplier Proteintech Group Inc Supplier No. 152241AP150UL
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Description

Rabbit Polyclonal Antibody

Proteintech's NDUFS5 antibody 15224-1-AP is capable of detecting the 15 kDa protein in Western blotting.

Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH that is produced in the Krebs cycle, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFS5 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 5), also designated NADH-ubiquinone oxidoreductase 15 kDa subunit, is a 106 amino acid protein that is suggested to not be involved in catalysis. NDUFS5 is expressed ubiquitously in human tissues, with a relative higher expression in human heart, skeletal muscle, liver, kidney and fetal heart.

Specifications

Antigen NDUFS5
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.18 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NDUFS5
Gene Accession No. O43920, Q99LY9
Gene Alias CI 15 kDa, Complex I 15 kDa, NDUFS5
Gene Symbols Ndufs5
Host Species Rabbit
Immunogen NDUFS5 Fusion Protein Ag7441
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 362588, 4725, 595136
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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