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Invitrogen™ NDUFV3 Polyclonal Antibody
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Catalog No. PIPA554082
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100 μL
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PIPA554082 100 μL
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Catalog No. PIPA554082 Supplier Invitrogen™ Supplier No. PA554082
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PPLPRKETSG TQGIEGHLKG GQAIVEDQIP PSNLETVPVE NNHGFHEKTA ALKLEAEGEA MEDAAAPGDD RGGTQEPAPV PAEPFDNTTY KNLQHHDYST YTFLDLNLEL SKFRMP Highest antigen sequence identity to the following orthologs: Mouse - 49%, Rat - 48%.

Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH that is produced in the Krebs cycle, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any one of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFV3 (NADH dehydrogenase [ubiquinone] flavoprotein 3), also designated NADH-ubiquinone oxidoreductase 9 kDa subunit or CI-9kD, is a 108 amino acid protein that is believed to not be involved in catalysis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NDUFV3
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NDUFV3
Gene Accession No. P56181
Gene Alias 1500032D16Rik; CI-10k; CI-9KD; complex I 10kDa subunit; complex I, mitochondrial respiratory chain, 10-kD subunit; complex I-9kD; Mipp65; mitochondrial NADH oxidoreductase-like protein; NADH dehydrogenase (ubiquinone) flavoprotein 3; NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa; NADH dehydrogenase (ubiquinone) flavoprotein 3-like; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial; NADH:ubiquinone oxidoreductase subunit V3; NADH-ubiquinone oxidoreductase 9 kD subunit; NADH-ubiquinone oxidoreductase 9 kDa subunit; NADH-ubiquinone oxidoreductase flavoprotein 3; NADH-ubiquinone oxidoreductase flavoprotein 3, 10kD; NDUFV3; Ndufv3l; renal carcinoma antigen NY-REN-4
Gene Symbols NDUFV3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NDUFV3. Recombinant protein control fragment (Product #RP-102242).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4731
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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