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  5. Tocris Bioscience™ Nebivolol hydrochloride

Tocris Bioscience™ Nebivolol hydrochloride
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Catalog No. 351710
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35-171-0 10 mg
35-175-0 50 mg
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Catalog No. 35-171-0 Supplier Tocris Bioscience™ Supplier No. 3517/10
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Description

Highly selective β1-adrenoceptor antagonist

Highly selective β1-adrenoceptor antagonist (Ki values are 0.88, 20, 44, 700, 1160, 2400 and 4000 nM at β1, 5-HT1A, β2, 5-HT2, α1, H1 and D2 receptors respectively). Induces vasodilation via a nitric oxide- and cGMP-dependent mechanism (EC50 = 11.36 μM in renal arteries) and displays antihypertensive activity in vivo. GRK/β -arrestin biased agonist at the β2 adrenoceptor.

Chemical Identifiers

CAS 152520-56-4
Molecular Formula C22H26ClF2NO4

Specifications

Quantity 10 mg
Formula Weight 441.9
Purity >98%
Molecular Weight (g/mol) 445.924
Chemical Name or Material Nebivolol hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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