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Invitrogen™ Nebulin Polyclonal Antibody
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Catalog No. PIPA553457
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100 μL
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PIPA553457 100 μL
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Catalog No. PIPA553457 Supplier Invitrogen™ Supplier No. PA553457
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DTPDMLRAKN ATQILNEKEY KRDLELEVKG RGLNAMANET PDFMRARNAT DIASQIKYKQ SAEMEKANFT SVVDTPEIIH AQQVKNLSSQ KKYKEDAEKS MSYYETVLDT PEIQRVRENQ KNFSLLQYQC DL Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 98%.

This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein. The encoded protein contains approximately 30-amino acid long modules that can be classified into 7 types and other repeated modules. Protein isoform sizes vary from 600 to 800 kDa due to alternative splicing that is tissue-, species-, and developmental stage-specific. Of the 183 exons in the nebulin gene, at least 43 are alternatively spliced, although exons 143 and 144 are not found in the same transcript. Mutations in this gene are associated with recessive nemaline myopathy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nebulin
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NEB
Gene Accession No. P20929
Gene Alias AI595938; DKFZp686C1456; FLJ11505; FLJ36536; FLJ39568; FLJ39584; NEB; NEB177D; nebulin; NEM2; nemaline myopathy type 2
Gene Symbols NEB
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Nebulin. Recombinant protein control fragment (Product #RP-102106).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4703
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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