Invitrogen™ NECAB3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544822

Catalog No. PIPA544822

Description

Peptide sequence: MACAGLLTVC LLRPPAPQPQ PQTPRHPQLA PDPGPAGHTL FQDVFRRADK Sequence homology: Cow: 79%; Dog: 90%; Horse: 77%; Human: 100%; Mouse: 83%; Pig: 90%; Rat: 90%; Yeast: 100%.

The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: NECAB3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NECAB3
• Gene Alias: 2900010M17Rik; AI853434; amyloid beta (A4) precursor protein-binding family A member 1 binding protein; amyloid beta (A4) precursor protein-binding, family A, member 1 binding protein; amyloid beta (A4) precursor protein-binding, family A, member 2 binding protein; amyloid beta A4 protein-binding family A member 2-binding protein; Amyloid-beta A4 protein-binding family A member 2-binding protein; Apba2bp; dJ63M2.4; dJ63M2.5; EFCBP3; EF-hand calcium binding protein 3; mXB51; NECAB3; Nek2-interacting protein 1; neuronal calcium-binding protein 3; neuronal calcium-binding protein NECAB3; NIP1; N-terminal EF-hand calcium binding protein 3; N-terminal EF-hand calcium-binding protein 3; STIP3; synaptotagmin interacting protein 2; synaptotagmin interacting protein STIP3; SYTIP2; X11L-binding protein 51; XB51
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 63941
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q96P71
• Gene Symbols: NECAB3
• Immunogen: Synthetic peptide directed towards the N-terminal of human NECAB3 (aa 1-50).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov