Invitrogen™ NECAB3 Polyclonal Antibody

Catalog No.	Quantity
PIPA584844	100 μL

Catalog No. PIPA584844 Supplier Invitrogen™ Supplier No. PA584844

Description

Rabbit Polyclonal Antibody

Immunogen sequence: SSEAEMQWRL QVNRLQELID QLECKVRAVG PGPHKGGPSW YPPEPGPCWR PGPHSVPSQA PRLEPLREED LAK Highest antigen sequence indentity to the following orthologs: Mouse - 48%, Rat - 48%.

The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: NECAB3
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 0.3 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: NECAB3
• Gene Accession No.: Q96P71
• Gene Alias: 2900010M17Rik; AI853434; amyloid beta (A4) precursor protein-binding family A member 1 binding protein; amyloid beta (A4) precursor protein-binding, family A, member 1 binding protein; amyloid beta (A4) precursor protein-binding, family A, member 2 binding protein; amyloid beta A4 protein-binding family A member 2-binding protein; Amyloid-beta A4 protein-binding family A member 2-binding protein; Apba2bp; dJ63M2.4; dJ63M2.5; EFCBP3; EF-hand calcium binding protein 3; mXB51; NECAB3; Nek2-interacting protein 1; neuronal calcium-binding protein 3; neuronal calcium-binding protein NECAB3; NIP1; N-terminal EF-hand calcium binding protein 3; N-terminal EF-hand calcium-binding protein 3; STIP3; synaptotagmin interacting protein 2; synaptotagmin interacting protein STIP3; SYTIP2; X11L-binding protein 51; XB51
• Gene Symbols: NECAB3
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human NECAB3. Recombinant protein control fragment (Product #RP-108568).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 63941
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG