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  5. Tocris Bioscience™ Necrostatin-1

Tocris Bioscience™ Necrostatin-1
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Catalog No. 232450
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Catalog No. Quantity
23-245-0 50 mg
23-241-0 10 mg
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Catalog No. 23-245-0 Supplier Tocris Bioscience™ Supplier No. 2324/50
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Description

RIP1 kinase inhibitor; inhibits necroptosis

ATP-competitive, allosteric inhibitor of receptor-interacting protein kinase 1 (RIPK1) (EC50 = 182 nM). Blocks non-apoptotic cell death via inhibition of a specific cellular pathway, necroptosis, which leads to necrosis (EC50 = 494 nM). Reduces ischemic brain injury in a mouse model of stroke.

Chemical Identifiers

CAS 4311-88-0
Molecular Formula C13H13N3OS

Specifications

Quantity 50 mg
Formula Weight 259.33
Purity 98%
Molecular Weight (g/mol) 259.327
Chemical Name or Material Necrostatin-1

Safety and Handling

Recommended Storage Store at Room Temperature
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