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Invitrogen™ Nectin 1 Polyclonal Antibody
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Catalog No. PIPA582938
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PIPA582938 100 μL
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Catalog No. PIPA582938 Supplier Invitrogen™ Supplier No. PA582938
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DSMYGFIGTD VVLHCSFANP LPSVKITQVT WQKSTNGSKQ NVAIYNPSMG VSVLAPYRER VEFLRPSFTD GTIRLSRLEL EDEGVYICEF ATFPTGNRES QLNLTVMAKP TNWIEGTQAV LRAKKGQDD Highest antigen sequence indentity to the following orthologs: Mouse - 91%, Rat - 90%.

This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nectin 1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Nectin1
Gene Accession No. Q15223
Gene Alias AI835281; AW549174; CD111; CLPED1; ectodermal dysplasia 4 (Margarita Island type); ED4; herpes simplex virus type 1 sensitivity; herpes virus entry mediator C; Herpesvirus entry mediator C; herpesvirus Ig-like receptor; HIgR; HV1S; Hvec; nectin 1; nectin cell adhesion molecule 1; nectin); Nectin1; nectin-1; nectin-1 alpha; nectin-1 delta; OFC7; poliovirus receptor-like 1; poliovirus receptor-related 1; poliovirus receptor-related 1 (herpesvirus entry mediator C; poliovirus receptor-related 1 (herpesvirus entry mediator C); poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin); poliovirus receptor-related protein 1; PRR; PRR1; PVRL1; PVRR; PVRR1; SK-12
Gene Symbols Nectin1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NECTIN1. Recombinant protein control fragment (Product #RP-90093).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5818
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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