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Invitrogen™ Nectin 4 Recombinant Human Monoclonal Antibody (6D3)
Human Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA549975
Description
Nectin 4 Recombinant Monoclonal Antibody for ELISA
Nectin 4 (PVRL4) is a gene located on chromosome 1q23.3 that encodes a member of the nectin family of cellular adhesion molecules. These proteins are primarily involved in forming adherens junctions between epithelial cells, contributing to tissue integrity and maintenance in various tissues, including the skin, lungs, and mammary glands. Nectin 4 is highly expressed during embryonic development and is crucial for processes like tissue morphogenesis and repair. It acts as a ligand for the poliovirus receptor-related family and participates in cell signaling pathways that influence cell proliferation and survival. In the context of cancer, Nectin 4 is often upregulated, particularly in breast, ovarian, and lung cancers, where its expression is associated with tumor progression, metastasis, and poor prognosis. This makes Nectin 4 a potential target for therapeutic interventions and a candidate biomarker for cancer diagnosis and monitoring.
Specifications
Nectin 4 | |
Recombinant Monoclonal | |
1 mg/mL | |
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4 | |
Q96NY8 | |
NECTIN4 | |
Recombinant Human NECTIN4 protein. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
ELISA | |
6D3 | |
Unconjugated | |
NECTIN4 | |
1200017F15Rik; EDSS1; ig superfamily receptor LNIR; LNIR; nectin 4; nectin cell adhesion molecule 4; NECTIN4; Nectin-4; poliovirus receptor-related 4; poliovirus receptor-related protein 4; Processed poliovirus receptor-related protein 4; PRR4; Pvrl4; RGD1559826 | |
Human | |
Affinity chromatography | |
RUO | |
81607 | |
-20°C or -80°C if preferred | |
Liquid |
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