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NEDD5 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987439
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100 μL
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50-198-7439 100 μL
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Catalog No. 50-198-7439 Supplier Bioss Supplier No. BS6704R
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Description

Rabbit Polyclonal Antibody

Septin 2 is a filament-forming cytoskeletal GTPase. Septin 2 is required for normal organization of the actin cytoskeleton and plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. It is required for the progression through mitosis, and it forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, Septin 2 may be required for chromosome segregation and spindle elongation. Septin 2 also plays a role in ciliogenesis and collective cell movements.

Specifications

Antigen NEDD5
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SEPTIN2
Gene Accession No. Q15019
Gene Alias 2-Sep; AW208991; DIFF6; hNedd5; KIAA0158; mKIAA0158; NEDD5; Nedd-5; Neural precursor cell expressed developmentally down-regulated protein 5; neural precursor cell expressed, developmentally down-regulated 5; neural precursor cell expressed, developmentally down-regulated gene 5; Pnutl3; SEPT2; septin 2; SEPTIN2; Septin-2; Vascular endothelial cell specific protein 11; Vesp11
Gene Symbols SEPTIN2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Septin 2/NEDD5.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4735
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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