Invitrogen™ NEDD8 Polyclonal Antibody

Catalog No.	Quantity
PIPA5102372	100 μL

Catalog No. PIPA5102372

Supplier: Invitrogen™ PA5102372

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NEDD8.

NEDD8 is a ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.

Specifications

• Antigen: NEDD8
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: Nedd8
• Gene Accession No.: P29595, Q15843, Q71UE8
• Gene Alias: nedd8; NEDD-8; NEDD8 ubiquitin like modifier; nedd8.L; nedd8.S; neddylin; Neural precursor cell expressed developmentally down-regulated protein 8; neural precursor cell expressed, developmentally down-regulated 8; neural precursor cell expressed, developmentally down-regulated 8 L homeolog; neural precursor cell expressed, developmentally down-regulated 8 S homeolog; neural precursor cell expressed, developmentally down-regulated gene 8; neural precursor cell-expressed developmentally down-regulated; Rub1; si:zc14a17.5; ubiquitin; ubiquitin-like protein Nedd8; XELAEV_18007009mg
• Gene Symbols: Nedd8
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human NEDD8(Accession Q15843), corresponding to amino acid residues M1-N51.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 18002, 25490, 4738
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG