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NEFH/NEFL Mouse anti-Human, Clone: SPM145, Abnova™

Catalog No. 89934675 Shop All Abnova Corporation Products
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89-934-675 100 μg
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Catalog No. 89-934-675 Supplier Abnova Corporation Supplier No. MAB13211
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Description

Mouse monoclonal antibody raised against native human NEFH/NEFL.

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq]

Specifications

Antigen NEFH/NEFL
Applications Flow Cytometry, Immunohistochemistry (PFA fixed)
Classification Monoclonal
Clone SPM145
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against native human NEFH/NEFL.
Dilution Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Alias NFH
Gene Symbols NEFH
Host Species Mouse
Immunogen Semi-purified NEFH/NEFL from human spinal cord.
Purification Method Protein G purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4744/4747
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG1
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