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NEFH/NEFL Mouse anti-Human, Clone: SPM145, Abnova™

Mouse monoclonal antibody raised against native human NEFH/NEFL.

Manufacturer:  Abnova Corporation MAB13211

Catalog No. 89-934-675


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Description

Description

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq]

Specifications

Specifications

NEFH/NEFL
SPM145
Mouse monoclonal antibody raised against native human NEFH/NEFL.
In 10mM PBS (0.05% BSA, 0.05% sodium azide).
NFH
Mouse
IgG1
100 ug
Store at 4°C.
Monoclonal
Human
Flow Cytometry, Immunohistochemistry (PFA fixed)
Unconjugated
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL) The optimal working dilution should be determined by the end user.
Liquid
NEFH
Semi-purified NEFH/NEFL from human spinal cord.
Protein G purification
RUO
Primary
4744/4747
SDS
Documents
Product Certifications
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