NEFH/NEFL Mouse anti-Human, Clone: SPM145, Abnova™
Mouse monoclonal antibody raised against native human NEFH/NEFL.
Manufacturer: Abnova Corporation MAB13211
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq]
|Mouse monoclonal antibody raised against native human NEFH/NEFL.|
|In 10mM PBS (0.05% BSA, 0.05% sodium azide).|
|Store at 4°C.|
|Flow Cytometry, Immunohistochemistry (PFA fixed)|
|Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL) The optimal working dilution should be determined by the end user.|
|Semi-purified NEFH/NEFL from human spinal cord.|
|Protein G purification|
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