NEFL Mouse anti-Human, Clone: OTI2F5, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF801223

Catalog No. 50-166-5500

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Involved in the maintece of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predomitly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-L is the light or low molecular weight microfilament subunit and runs on SDS-PAGE gels at approximately 70 kDa. Neurofilament are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predomitly of three major proteins called NF-L, NF-M and NF-H. NF-H is the heavy or high molecular weight microfilament subunit and runs on SDS-PAGE gels in the range 180-220kDa, with some variation in different species.

Specifications

• Antigen: NEFL
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: NEFL
• Gene Alias: CMT1F, CMT2E, NF-L, NF68, NFL, PPP1R110
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4747
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI2F5
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P07196
• Gene Symbols: NEFL
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-360 of human NEFL produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b