Invitrogen™ NEK2 Recombinant Rabbit Monoclonal Antibody (5O0A1)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535693

Catalog No. PIMA535693

Description

Immunogen sequence: MPSRAEDYEV LYTIGTGSYG RCQKIRRKSD GKILVWKELD YGSMTEAEKQ MLVSEVNLLR ELKHPNIVRY YDRIIDRTNT TLYIVMEYCE GGDLASVITK.

NEK2 is involved in cell cycle regulation and is essential for faithful chromosome segregation. NEK2 is a gene that encodes for a serine/threonine-protein kinase. This protein plays a crucial role in the regulation of mitosis and is primarily located in the centrosome. During the G1 phase, the protein is undetectable, but its levels progressively increase throughout the S phase, reaching their peak in late G2 phase. The gene has several alternatively spliced transcript variants that encode different isoforms with distinct C-termini. NEK2 is associated with several diseases, including Retinitis Pigmentosa 67 and Retinitis Pigmentosa.

Specifications

• Antigen: NEK2
• Classification: Recombinant Monoclonal
• Concentration: 0.7 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O35942, P51955
• Gene Symbols: NEK2
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NEK2 (P51955).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 5O0A1
• Conjugate: Unconjugated
• Gene: NEK2
• Gene Alias: AA617254; C77054; HSPK 21; HsPK21; NEK 2; NEK 2A; Nek2; Nek2 kinase; NEK2A; Never in mitosis A-related kinase 2; NIMA - related expressed kinase 2; NIMA (never in mitosis gene a)-related expressed kinase 2; NIMA (never in mitosis gene a)-related kinase 2; NIMA related kinase 2; nimA-like protein kinase 1; NIMA-related expressed kinase 2; NIMA-related kinase 2; nimA-related protein kinase 2; NLK 1; NLK1; PPP1R111; protein phosphatase 1, regulatory subunit 111; RP67; Serine/threonine-protein kinase Nek2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114482, 18005, 4751
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid