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Invitrogen™ NEK2 Polyclonal Antibody
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Catalog No. PIPA592416
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100 μL
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PIPA592416 100 μL
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Catalog No. PIPA592416 Supplier Invitrogen™ Supplier No. PA592416
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MPSRAEDYEV LYTIGTGSYG RCQKIRRKSD GKILVWKELD YGSMTEAEKQ MLVSEVNLLR ELKHPNIVRY YDRIIDRTNT TLYIVMEYCE GGDLASVITK GTKERQYLDE EFVLRVMTQL TLALKECHRR SDGGH; Positive Samples: Mouse testis, Mouse thymus; Cellular Location: Chromosome, Cytoplasm, Nucleus, centromere, centromere, centrosome, cytoskeleton, kinetochore, microtubule organizing center, nucleolus, spindle pole.

NEK2 is involved in cell cycle regulation and is essential for faithful chromosome segregation. NEK2 is a gene that encodes for a serine/threonine-protein kinase. This protein plays a crucial role in the regulation of mitosis and is primarily located in the centrosome. During the G1 phase, the protein is undetectable, but its levels progressively increase throughout the S phase, reaching their peak in late G2 phase. The gene has several alternatively spliced transcript variants that encode different isoforms with distinct C-termini. NEK2 is associated with several diseases, including Retinitis Pigmentosa 67 and Retinitis Pigmentosa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NEK2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.85 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NEK2
Gene Accession No. O35942, P51955
Gene Alias AA617254; C77054; HSPK 21; HsPK21; NEK 2; NEK 2A; Nek2; Nek2 kinase; NEK2A; Never in mitosis A-related kinase 2; NIMA - related expressed kinase 2; NIMA (never in mitosis gene a)-related expressed kinase 2; NIMA (never in mitosis gene a)-related kinase 2; NIMA related kinase 2; nimA-like protein kinase 1; NIMA-related expressed kinase 2; NIMA-related kinase 2; nimA-related protein kinase 2; NLK 1; NLK1; PPP1R111; protein phosphatase 1, regulatory subunit 111; RP67; Serine/threonine-protein kinase Nek2
Gene Symbols NEK2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human NEK2 (NP_0011911121).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18005, 4751
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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