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Invitrogen™ NEK2 Recombinant Rabbit Monoclonal Antibody (JE37-74)
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Catalog No. FEMA550807
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100 μL
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FEMA550807 100 μL
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Catalog No. FEMA550807 Supplier Invitrogen™ Supplier No. MA550807
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Rabbit Recombinant Monoclonal Antibody

Positive control: A549 cell lysate, Hela cell lysate. Predicted band size: 52 kDa Subcellular Location: Nucleus, nucleolus, Cytoplasm.

NEK2 is involved in cell cycle regulation and is essential for faithful chromosome segregation. NEK2 is a gene that encodes for a serine/threonine-protein kinase. This protein plays a crucial role in the regulation of mitosis and is primarily located in the centrosome. During the G1 phase, the protein is undetectable, but its levels progressively increase throughout the S phase, reaching their peak in late G2 phase. The gene has several alternatively spliced transcript variants that encode different isoforms with distinct C-termini. NEK2 is associated with several diseases, including Retinitis Pigmentosa 67 and Retinitis Pigmentosa.
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Specifications

Antigen NEK2
Applications Western Blot
Classification Recombinant Monoclonal
Clone JE37-74
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene NEK2
Gene Accession No. P51955
Gene Alias AA617254; C77054; HSPK 21; HsPK21; NEK 2; NEK 2A; Nek2; Nek2 kinase; NEK2A; Never in mitosis A-related kinase 2; NIMA - related expressed kinase 2; NIMA (never in mitosis gene a)-related expressed kinase 2; NIMA (never in mitosis gene a)-related kinase 2; NIMA related kinase 2; nimA-like protein kinase 1; NIMA-related expressed kinase 2; NIMA-related kinase 2; nimA-related protein kinase 2; NLK 1; NLK1; PPP1R111; protein phosphatase 1, regulatory subunit 111; RP67; Serine/threonine-protein kinase Nek2
Gene Symbols NEK2
Host Species Rabbit
Immunogen Synthetic peptide within Human NEK2 aa 1-50/445.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4751
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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