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NEK7 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501572631
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50-157-2631 100 μL
50-157-2632 10 μL
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Catalog No. 50-157-2631 Supplier Bethyl Laboratories, Inc Supplier No. IHC00739
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Bovine, Dog, Horse, Rabbit, Pig, Panda, Orangutan, Chimpanzee, Northern white-cheeked gibbon and

NEK9, a NEK type protein kinase, regulates chromosome alignment and segregation in mitosis. The protein has a N-terminal NIMA-like catalytic domain, a central domain with homology to the guanine nucleotide exchange factor for the GTPase Ran (RCC1), and a C-terminal coiled-coil domain. It is phosphorylated by active p34(Cdc2) and is capable of autophosphorylation and oligomerization. The activated protein binds Nek6 and RCC1, and has been shown to associate with the human homolog of the Drosophila protein Bicaudal D (Bicd2) in vivo and to phosphorylate this coiled-coil protein in vitro. NEK9 expression has been documented in normal human brain. ESTs have been isolated from several tissue libraries, including normal bone, lymph and thymus and cancerous cervix, eye, lymph and placenta.

Specifications

Antigen NEK7
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene NEK7
Gene Accession No. Q8TDX7
Gene Alias Never In Mitosis Gene A-Related Kinase 9
Gene Symbols NEK7
Host Species Rabbit
Immunogen Between 1 and 50
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140609
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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