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NEK7 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987990
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100 μL
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50-198-7990 100 μL
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Catalog No. 50-198-7990 Supplier Bioss Supplier No. BS7758R
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Rabbit Polyclonal Antibody

NEK9, a NEK type protein kinase, regulates chromosome alignment and segregation in mitosis. The protein has a N-terminal NIMA-like catalytic domain, a central domain with homology to the guanine nucleotide exchange factor for the GTPase Ran (RCC1), and a C-terminal coiled-coil domain. It is phosphorylated by active p34(Cdc2) and is capable of autophosphorylation and oligomerization. The activated protein binds Nek6 and RCC1, and has been shown to associate with the human homolog of the Drosophila protein Bicaudal D (Bicd2) in vivo and to phosphorylate this coiled-coil protein in vitro. NEK9 expression has been documented in normal human brain. ESTs have been isolated from several tissue libraries, including normal bone, lymph and thymus and cancerous cervix, eye, lymph and placenta.

Specifications

Antigen NEK7
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene NEK7
Gene Accession No. Q8TDX7
Gene Alias 2810460C19Rik; AU020186; NEK7; Never in mitosis A-related kinase 7; NIMA (never in mitosis gene a)-related expressed kinase 7; NIMA (never in mitosis gene a)-related kinase 7; NIMA related kinase 7; NIMA-related expressed kinase 7; NIMA-related kinase 7; NimA-related protein kinase 7; Serine/threonine-protein kinase Nek7
Gene Symbols NEK7
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human NEK7.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140609
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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