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NEK8 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988035
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50-198-8035 100 μL
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Catalog No. 50-198-8035 Supplier Bioss Supplier No. BS7815R
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Description

Rabbit Polyclonal Antibody

Required for renal tubular integrity. May regulate local cytoskeletal structure in kidney tubule epithelial cells. May regulate ciliary biogenesis through targeting of proteins to the cilia.Defects in NEK8 are the cause of nephronophthisis type 9 (NPHP9) [MIM:613824]. NPHP9 is an autosomal recessive disorder resulting in end-stage renal disease. It is a progressive tubulo-interstitial kidney disorder histologically characterized by modifications of the tubules with thickening of the basement membrane, interstitial fibrosis and, in the advanced stages, medullary cysts.

Specifications

Antigen NEK8
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene NEK8
Gene Accession No. Q86SG6
Gene Alias 4632401F23Rik; b2b1449Clo; Jck; juvenile cystic kidney; NEK 8; NEK12A; NEK8; nephrocystin 9; Never in mitosis A-related kinase 8; NIMA (never in mitosis gene a)- related kinase 8; NIMA (never in mitosis gene a)-related expressed kinase 8; NIMA related kinase 8; NIMA-family kinase NEK8; NIMA-related expressed kinase 8; NIMA-related kinase 12a; NIMA-related kinase 8; Nima-related protein kinase 12a; NimA-related protein kinase 8; NPHP9; RHPD2; Serine/threonine-protein kinase Nek8; serine/thrionine-protein kinase NEK8
Gene Symbols NEK8
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human NEK8.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 284086
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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